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In some cases a B12 deficiency is linked with symptoms like nausea, bloating, or loss of appetite

Phosphoglycerate dehydrogenase (PHGDH) is the first enzyme branching from glycolysis in the serine biosynthesis which involved in one-carbon metabolism to supply S-adenosyl methionine (SAM) (120)

doi: 10.3389/fendo.2022.839005

Delivery strategies of amphotericin B for invasive fungal infections
