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[66] [67] However, a 2025 meta-analytic systematic review of 113 randomized controlled trials found that stimulant medications were the only intervention with robust short-term efficacy, and were associated with lower all-cause treatment discontinuation rates than non-stimulant medications (e.g., atomoxetine)

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(2014) 10:e1004372

152,153 Medications for fibromyalgia have been shown to be, at best, moderately effective in fewer than half of patients