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Three ml of blood was placed in heparinized tubes and centrifuged at 3000 rpm for 10 min at 4C

Without sufficient magnesium, the enzyme ATPase cannot efficiently break down ATP to release its stored energy, leaving cells functionally starved even if nutrient intake is adequate

doi: 10.1021/tx100333r

Zinc can also influence vesicle formation and SNARE-dependent trafficking by contributing to the ionic environment that supports coat assembly and membrane fusion reactions 79

However, until now, few drugs have been used in clinical cases (Table 1), which is due to the heterogeneity of tumors and their complex regulatory mechanisms