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One major limitation is the dependence on plant materials that are often geographically restricted or seasonally available

Considering an enormous number of M-L combinations in the chemical space, it is impractical to perform measurements of the overall stability constants for all candidates to find promising ligands

B.Abdel-MoeminA

JCSM Rapid Communications, 3 (1), 25-37

P., Kosmicki, J., Deluca, T
