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2-(2-Cholesteroxyethoxyl)ethyl-3-S-glutathionylpropionate (COXP) for brain-targeting liposomes

doi: 10.1177/1533317517722005 133 CraftSBakerLDMontineTJMinoshimaSWatsonGSClaxtonAet al

Current research explores roles in diabetes, heart health, and neurodegeneration

This disruption causes a redox imbalance, leading to membrane lipid peroxidation, reactive oxygen species (ROS) accumulation, and ultimately, iron-dependent oxidative cell death [3]

Due to the peculiarities of the expression location of GPX2, it is considered the first barrier for mammals to prevent the absorption of hydroperoxides produced by food.Studies have found that the expression level of selenoprotein in mammals is not balanced with the supply of selenium
