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Eli Lilly submitted orforglipron to the FDA for approval as an obesity treatment in 2025

doi: 10.1016/J.TOX.2021.152780 8

Loguercio C, De Girolamo V, de Sio I, Tuccillo C, Ascione A, Baldi F, et al

This is compounded by the downregulation of endocytic recycling proteins, preventing the salvage of damaged MBP [71]
