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Gibbs free barrier and released energies involved in hydrogen abstraction from the different sites of glutathione by an OH radical were studied at the B3LYP/6-31G(d,p), B3LYP/AUG-cc-pVDZ, M06/AUG-cc-pVDZ, M06-2X/AUG-cc-pVDZ levels of density functional theory

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Among the early responding pathways, the degradation of branched-chain amino acid was increased, whereas the one carbon folate metabolism was decreased

These include diabetes, inflammatory bowel disease, various skin illnesses, immunological and allergy problems, cardiovascular diseases, and neurological disorders like aging, dementia, and Alzheimer's

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