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This biochemical profile correlates strongly with worse clinical progression, higher inflammatory markers, and the onset of severe neurological sequelae

Org Biomol Chem 2:20922102 Williams PG, Yoshida WY, Moore RE, Paul VJ (2002) Isolation and structure determination of obyanamide, a novel cytotoxic cyclic depsipeptide from the marine cyanobacterium Lyngbya confervoides

Yeast Orp1 contains a peroxidatic cysteine (pK a of 5.1 (Ma et al ., 2007)) that, via its thiolate state, attacks H 2 O 2 , leading to sulfenylation and subsequent disulfide formation

Independent literature is thin

On the one hand, for ferroptosis-promoting power that boosts the generation and accumulation of lipid peroxides, there are mainly three resources: lipid metabolism, iron metabolism, and mitochondrial metabolism