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Anecdotally, many researchers working on specific, localized injuries prefer localized administration, believing it provides a more targeted and potent effect

If you are on a microdosing protocol at 1 mg or 1.25 mg per dose, a 0.3 mL syringe gives you the most accurate draws

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As a rapid and sustained effect (and final suited outcome), the raised intraocular pressure was avoided/counteracted providing the application time was before induction or in the already advanced course