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The tripeptide has high affinity for copper, and most of GHK's documented biological activity in the published literature is mediated by the copper complex particularly its effects on antioxidant enzyme activity, ECM remodeling, and gene expression
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doi: 10.1562/0031-8655(2001)074 2.0.CO;2
mansoni In mammals (upper pathway), electrons from NADPH are transferred to an oxidoreductase flavoenzyme, either thioredoxin reductase (TrxR) or glutathione reductase (GR)
