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These nanosheets significantly improved neuronal survival, reduced oxidative damage, preserved dopaminergic neurons, and inhibited synuclein aggregation (Mamashli et al
Asmat U, Abad K, Ismail K
In a similar study, the pivotal role for the IGF-1 in insulin sensitivity has received further support from liver-specific IGF-1 KO mice which exhibited overt insulin resistance and hyperinsulinaemia that was reversed by the administration of IGF-1 [161]
10.1002/oby.22090 17 CrosthwaitJ.SyeddanS.AtlasE
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