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Preclinical studies in obese mouse models showed that NNMT inhibition with 5-Amino-1MQ reduced adipocyte size and body weight without changes to food intake, suggesting effects on energy expenditure rather than appetite

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We summary association of NNMT expression with clinicopathological characteristics, the result of NNMT gene silence in patients with various cancers and the related signal transduction system ( Table 1 )

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Metabolic characterization of hepatocellular carcinoma using nontargeted tissue metabolomics