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93,94 IL-6 is crucial for innate and adaptive immunity, efficient pathogen clearance, and physiological functions such as regulation of acute-phase response, hematopoiesis, lipid homeostasis, metabolism, and neural development

41 HMGB1 is known to promote the release of histones from neutrophils and to enhance their ability to bind to bacterial membranes, thereby increasing the efficacy of NETs in killing invading microorganisms

-Glutamyl transpeptidaseits role in hepatocarcinogenesis

A multicenter, double-blind clinical trial proved that the course of GO could be improved after six months continuous Se supplementation (100mcg twice a day), and the treatment effects were still maintained after six months [55]

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