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[DOI] [PubMed] [Google Scholar] 42.Butterworth RF Pathophysiology of hepatic encephalopathy: the concept of synergism

The findings that GCLC desuccinylation activates its enzymatic activity and subsequent GSH synthesis prompted us to search for the responsible desuccinylase

This impacts the interaction of histones with the negatively charged DNA and triggers DNA unwinding, nuclear expansion and chromatin condensation

Blood 108(11):254, 2006
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However, the effect of these differences on neuronal development and function remains unknown [41]
