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For instance, pharmacological agents that activate mitochondrial biogenesis pathways, such as peroxisome PGC-1, have shown potential in preclinical studies to improve mitochondrial function and protect against both cardiovascular and neurological disorders

Resveratrol and vascular health: evidence from clinical studies and mechanisms of actions related to its metabolites produced by gut microbiota

Research indicates that iron overload can lead to increased ROS production, which in turn disrupts mitochondrial membrane potential and promotes cell death pathways such as ferroptosis

Willow bark extract was used to develop aspirin, a well-known over-the-counter (OTC) pain reliever, fever reducer, and anti-inflammatory drug

M., Teixeira D