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A Phase I and pharmacokinetic study of VNP40101M, a novel sulfonylhydrazine alkylating agent, in patients with refractory leukemia

(288) demonstrated significantly reduced abundance of Akkermansia muciniphila in the intestines of DKD patients and db/db mice [Human observational + animal model evidence]

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In the study of N-methyl-D-aspartate (NMDA)-induced excitotoxicity, NMDA-treated rats received two-day prophylactic treatments of intraperitoneal EGCG injections (25 mg/kg) showed a higher cell density in the ganglion cell layer and thickness of Thy-1 immunoreactivity than those received intraperitoneal saline injections [110]