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Nakamura, N., Davis, K., Yan, J., Sloper, D

The theoretical basis of this study is as follows: OKGM and EW were cross-linked (based on the Schiff base) to form a self-repairing EK hydrogel, and the amino group of active peptide GHK-Cu can also form Schiff base bond with the aldehyde group of OKGM

Collect the supernatant to carry out the assay

These authors also established that the combination of APR-246 with different compounds and strategies inducing ferroptosis (pharmacological compounds, or genetic inactivation of SLC7A11 or GPX4) had a synergistic effect on the promotion of AML cell death, both in vitro and in vivo
