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NAC is one of the most studied non-hormonal supplements for endometriosis and is often considered foundational

137 As a sulfur-containing amino acid, it possesses two potential binding sites for metals and is capable of binding and sequestering divalent copper (II), trivalent iron (III), lead, mercury, and cadmium ions

Lau et al., 1984

Glutathione is an important and powerful antioxidant used to prevent oxidative stress and damage to cells in everything from winemaking to skincare products

Easier patient recruitment will allow analysis of larger and more representative populations, while subgroup analysis may help elucidate efficacy in a more selective green knee population