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Description
Vo H, Fu S, Hong D, Karp D, Piha-Paul S, Subbiah V, Janku F, Naing A, Yap TA , Ahnert J, Ajani J, Cartwright C, Naqvi M, Nogueras-Gonzalez G, Miller V, Palmer G, Vining D, Berry D, Meric-Bernstam F, Tsimberidou A

For the assessment of kidney injury severity (severity score), HE stained section images at 10 and 20 (2 at each magnification, for a total of 4 images per mouse) were graded from 0 (no damage) to 5 (most severe damage observed across the samples analyzed), based on the following parameters: (i) protein cast formation, (ii) visible tubular dilation, (iii) loss of proximal tubular cell polarization (no visible brush-border membranes) (iv) area affected (with single nephron damage to majority of the cortex with visual signs of injury)
Vitamin B5, Vitamin B6, and Vitamin B12 are studied as cofactor-support nutrients in enzymatic and metabolic systems

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Nolani had been drinking with friends at a bar in Manukau on February 6, 2025
