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immitis requires major transcriptional reprogramming with 22% of the entire genome being differentially expressed between the two conditions

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doi: 10.7554/eLife.47859 [DOI] [PMC free article] [PubMed] [Google Scholar] 86

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Mechanistic validation revealed that the use of the mTOR activator MHY1485 reversed the anti-inflammatory effects of hydrogen, thereby confirming its regulation of microglial transformation via the mTOR-autophagy axis and providing molecular evidence for hydrogen therapy in sepsis-associated encephalopathy (SAE) (Zhuang et al., 2020)

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