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The consistent O 2 supply from myoglobin facilitates normal cellular respiration and muscle function, especially in the context of high O 2 demand during which mitochondrial oxidative phosphorylation can become limited when the Po 2 falls below 3 Torr (Ref

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Sato E, Shick HE, Ransohoff RM, Hirose K (2010) Expression of fractalkine receptor CX3CR1 on cochlear macrophages influences survival of hair cells following ototoxic injury