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[PMC free article: PMC5460681] [PubMed: 28323934] 157

what the actual preclinical metabolic studies measured and found

This distinction is particularly useful in experimental designs where separation of adipose-specific signaling from systemic endocrine effects is required

Both are studied in relation to growth hormone release, but via different receptors Tesamorelin acts on GHRH receptors, while Ipamorelin acts through the ghrelin receptor pathway