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Portal and caval vein and abdominal aorta pressure recording Recordings were made in deeply anesthetized and laparatomized rats, with a cannula (BD Neoflon Cannula) connected to a pressure transducer (78534C MONITOR/ TERMINAL

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Gastrointestinal adverse events were reported by 72.5% of the patients in the cagrilintide-semaglutide group and 34.4% in the placebo group, most of which were transient and mild or moderate in severity