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This targeting has been demonstrated for the anti-MB protogenin (PRTG) CAR-T cells recognizing CSC of MB group 3 with a strong expression of PRTG (PRTG high ) and for the anti-PRTG blocking antibodies (329)

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For this purpose, an intravenous dose of 1.0 g/kg is administered under medical supervision, and GH levels are measured in the blood at intervals thereafter