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2017 meta-analysis: Five RCTs in 631 adults with insulin resistance showed that 23 g/day L-carnitine for 4 weeks to 12 months improved insulin resistance, with benefits at 12 months exceeding those at 3 months [3][42]

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doi: 10.2165/00007256-199622020-00005

There is a great deal of genetic variability in CYP family enzymatic activity, ranging from nonfunctional to increased function, representing another layer of complexity (45)

Analysis of the mean difference in total sperm motility showed that carnitines improved total sperm motility by 10.72% (95% CI 3.9417.50