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In one short-term pilot study, sodium dimethylbutyrate increased fetal hemoglobin levels in a dose-dependent manner (Kutlar 2012)

For example, tumor necrosis factor receptor 2 (TNFR2)-mediated costimulatory signals promote a glycolytic switch in human thymus-derived Treg cells [159] (Fig

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International scientific experts interviewed by Nature emphasized, there is no robust evidence or convincing studies to suggest there is any causal relationship (Pearson and Ledford, 2025[84])