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Description
This granular control helps some users manage side effects more effectively
- IGF-1 (trial data suggests no meaningful change
PMID 25382550
By weeks 3-4, users following a consistent caloric deficit may notice subtle changes: slightly looser-fitting clothing around the midsection, a minor reduction in waist measurement (0.5-1 cm), and potentially 0.5-1 kg of fat loss on top of what diet alone would produce
In big clinical trials, those who used semaglutide lost a lot of weight, more than those in the placebo group
