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Significance was determined by 2-way repeated measures ANOVA ( n = 5)

These effects may potentially provide a new therapeutic solution for stroke with specific beneficial effects on the CNS (i.e., reperfusion, amelioration of neuronal damage leading to recovery in the absence of memory, motor, and coordination deficits, and expression of specific genes in the hippocampus)

For example, berberine and palmatine have been reported can exert various pharmacological activities, such as anti-inflammatory, chondroprotective, and neuroprotective properties (Singh et al., 2019

Instead, because it is negatively charged, thus a stronger nucleophile it attacks the carbon while it is still connected to the bromine and breaks the CBr bond by making a new CS bond

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