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T cell costimulatory receptor CD28 is a primary target for PD-1mediated inhibition

doi: 10.1006/bbrc.2001.5956

Of note, such effective compensation in rodent brain includes the apparent ability to avoid a rise in mitochondrial ROS in Sod2- haploinsufficient and bi-genic mice, possibly due to rapid shuttling of O 2 into the cytosol for processing by alternate SOD activities (Fig