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The PCR results for DNA methylation were presented as the percentage of ChIP DNA relative to total input DNA (2 (Ct inputCt sample) ), with the Ct values detected by the indicated antibodies normalized to a Ct value obtained from control ChIP performed with nonspecific rabbit IgGs
[PubMed] [Google Scholar] 43.Bourgonje A.R., Abdulle A.E., Timens W., Hillebrands J.L., Navis G.J., Gordijn S.J., Bolling M.C., Dijkstra G., Voors A.A., Osterhaus A.D., et al
Tumor cell-derived lactate can polarize TAM into M2 type, activate the expression of VEGF and arginase 1 (ARG1) through the HIF1- signaling pathway in macrophages, and assist TAM to promote tumor growth (de la Cruz-Lpez et al., 2019
thus, the activation of Nrf2/ARE (antioxidant response element) pathway could stimulate a synergistic protective effect [47]
Circulation 55:375378
