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Thats a mechanistically different target than NSAIDs (nonsteroidal anti-inflammatory drugs), or corticosteroids, which partly explains why the compound has attracted interest in cases where conventional anti-inflammatory approaches have failed or created downstream problems

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Metformin reliably reduces B12 absorption over time, and this interaction is underappreciated by patients and some providers alike

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[DOI] [PMC free article] [PubMed] [Google Scholar] 286.Cummins T.R
