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doi: 10.1016/j.cell.2021.02.021

Attune Acoustic Focusing Cytometer (Life Technologies) was used to collect more than 100,000 events and data were analyzed using FlowJo Software (Tree Star, Ashland, USA)

Sirtuin Activation Sirtuins (SIRT1 through SIRT7) are enzymes that regulate gene expression, inflammation, and mitochondrial biogenesis

Current knowledge relies on: extrapolation from single-peptide studies theoretical mechanism overlap anecdotal or community-source speculation There is no controlled data establishing the safety of combined administration

J Korean Soc Food Sci Nutr 38(8):10161023 Heo K, Myoung KS, Lee JH, Huh CS (2009) Anti-obesitic effects of cathepsin s inhibitory fraction derived from Paecilomyces tenuipes in mice fed a high-fat diet