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They call it a gerozyme because it increases with aging and slows the bodys ability to repair joint tissue

Can J Physiol Pharmacol 90(5):617625

Lancet 382 (9886), 57
Sudhakar S, Chandran SV, Selvamurugan N, Nazeer RA (2020) Biodistribution and pharmacokinetics of thiolated chitosan nanoparticles for oral delivery of insulin in vivo

Avapritinib has been recently approved by the FDA for the treatment of indolent systemic mastocytosis (ISM)
