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Curcumin prevents testicular toxicity in rats treated with dexamethasone through the upregulation of the anti-apoptotic protein B-cell lymphoma 2 (Bcl-2) and improvement of spermatogenic disorders (Khorsandi et al., 2013)
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A 2- to 3-fold overdose from recommended doses can result in collapse or death of the animal due to circulatory or respiratory depression (Rector et al, 1996
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