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Both play a key role in regulating melanin production and skin cell renewalwhen low, they can trigger uneven pigmentation and dark patches Low Vitamin B12 disrupts DNA synthesis and melanocyte regulation, causing irregular melanin distribution

10.1016/j.pharmthera.2017.02.014 [DOI] [PMC free article] [PubMed] [Google Scholar] Hao Y., Li H., Ge X., Liu Y., Yin J., Li X., et al

H., Bell, R

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