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Description
The other two adducts, 2,3-dihydro-2-(N-formyl-2,3,6-triamino-4-oxopyrimidine-N-yl)-3-hydroxy AFB 1 and 8,9-dihydro-8-(2-amino-6-formamide-4-oxo-3,4-dihydropyrimid-5-yl formamido)-9-hydroxy AFB 1 (AFB 1 -FAPY and AFB 1 III respectively) are not spontaneously but appear to be removed catalytically by DNA repair enzymes
(PubMed) Chrysant SG, Chrysant GS
The flexibility of cartilage is due in large part to the presence of proteoglycans in the cartilage matrix
It also decreases the expression of microRNA-122 and PPAR- and increases AP1 and JNK phosphorylation [312]
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