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This can increase the risk of developing sarcopenia, a condition characterized by age-related muscle loss
The local production of apoE is likely a critical atheroprotective mechanism considering that areas of atherosclerotic lesions have limited accessibility to plasma apoA-1 and HDL (100,101,125)
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Insulin, for example, can enhance the expression of TMLH and BBOX, facilitating increased carnitine production during times of energy surplus