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Dogs with a B12 deficiency and/or anemia may have one or more of the following symptoms: lack of energy weakness reduced interest in play loss of appetite diarrhea weight loss loss of muscle mass confusion seizures What Causes B12 Deficiency in Dogs

For MS analysis, a positive ion mode (SIM) was used to monitor the m/z of dihexa at 527nm (dihexa with the addition of a sodium adduct) and the m/z of Nle-YI-(6) aminohexanoic amide and Nle 1 - AnglV (internal standards) at 513 and 541 , respectively (both with sodium adducts)

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Simons et al., 2005)

The intestinal microbiota supplies nutrients as well as protects the intestinal barrier against pathogens [79]