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In addition, there is a higher intensity of CD38 expression (measured by flow cytometry) in the more aggressive multi-hit variants, which allows further differentiation of the diseases and the use of CD38 as a biomarker for early diagnosis [14]
However, resistance mechanisms arise during the treatment with daratumumab, creating the necessity for new therapies
Unlike many newer peptides, AOD9604 was originally developed and taken through formal pharmaceutical trials before continuing on as a widely used laboratory research compound
Not for human consumption, therapeutic use or clinical applications
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