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Oxicam derivatives significantly impact macrophage-associated chemokine expression, which is crucial in colorectal cancer pathophysiology
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That potency is exactly why the dose is not started high: the entire point of a titration protocol is to introduce the compound at a low, well-tolerated level and raise it in slow, roughly four-week steps so the gastrointestinal system can adapt
Benarroch EE
Monroe, J
