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Mecanismos de accin (Explicacin cientfica) Transporte de cidos grasos de cadena larga al interior mitocondrial va CPT-1/CPT-2 El acceso de los cidos grasos a la matriz mitocondrial, donde ocurre la beta-oxidacin, es un proceso regulado por dos enzimas clave: la carnitina palmitoiltransferasa I (CPT-1), localizada en la membrana externa mitocondrial, y la CPT-2, situada en la cara interna

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However, persistent inflammation and oxidative stress can compromise the integrity of this barrier, particularly affecting the tight junction proteins such as ZO-1 and occludin, which are essential for maintaining the structural and functional integrity of the BTB (65)

2,3 This presents a problem, considering the size of this potential patient population

Depakote is a stabilized coordination compound (divalproex sodium) that tends to be gentler on the stomach and allows delayed- or extended-release dosing