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Description
Metformin may decrease intrinsic factor secretion from parietal cells, interfere with the calcium-dependent binding of the resulting intrinsic factor and B12 complex to receptors on the ileal lining, and change small intestinal motility, resulting in decreased B12 absorption

Placella will monitor your immediate reaction to ensure you have no adverse effects and that the treatment is effective

A total of 4275 patients with vitamin B12 deficiency were included in the final analysis


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