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However, small modifications to both the amino group and the methoxy group at position 5 of the benzothiazole core did not result in any significant increase or decrease in binding activity as measured by the CPMG assay, and no reliable LO-NMR K D data could be obtained for the analogues (Supplementary Table 1)

Porta, C., Moroni, M., Guallini, P., Torri, C

Eight-year weight losses with an intensive lifestyle intervention: the look AHEAD study
