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Targeting BRCAness Pathogenic mutations of BRCA1 / 2 are common in TNBC

Folate helps prevent neural tube defects, while iron supports red blood cell production

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Binding of apoptosis-linked gene-2-interacting protein X to its N-terminal region promotes secretion, whereas keratin 20 binding at this region inhibits secretion and thereby prevents ferroptosis in kidney tubular cells [152]