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Tissue Repair and Regenerative Medicine An emerging area of peptide therapeutics involves tissue repair and regenerative applications

[DOI] [PubMed] [Google Scholar] 22.Farid M., Demicco E.G., Garcia R., Ahn L., Merola P.R., Cioffi A., Maki R.G

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The intense, repetitive, and sustained noxious stimuli activate C-fiber nociceptors and cause a sustained release of fast neurotransmitter glutamate, which then binds to NMDA receptors on postsynaptic neurons in the dorsal horn of the spinal cord, inducing central sensitization (Woolf and Thompson, 1991)