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Wang ZJ, Churchman M, Campbell IG, Xu WH, Yan ZY, McCluggage WG, Foulkes WD, Tomlinson IP

J Biol Chem 254(4):12051210 Griffith OW, Meister A (1979) Potent and specific inhibition of glutathione synthesis by buthionine sulfoximine (S-n-butyl homocysteine sulfoximine)

Topical calcineurin inhibitors are hypothesized to cause alcohol-induced flushing by locally inhibiting acetaldehyde dehydrogenase, an enzyme necessary for alcohol metabolism

By localizing drugs at their desired site of action, systemic toxicity can be reduced, and treatment efficiency can be increased

GCN2iB acetate enhances the anticancer effect of ASNase against acute lymphoblastic leukemia
