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Conclusion The development of more VLP platforms such as PP7-N-Spytag (developed here) has the potential to add more VLPs in the vaccine toolbox of VLPs (in addition to AP205, norovirus, hepatitis B) which can be used in prime boost regimens or to develop new candidate vaccines against other infectious agents by displaying different antigens on different VLP platforms to minimize any potentials for anti-platform immune responses

Plasma rather than tissue samples were used for biochemical analysis, which may not accurately reflect local oxidative stress

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The glucose-6-phosphotase (G6Pase) complex, which localizes to the endoplasmic reticulum membrane, converts G6P to glucose, to maintain glucose and glycogen balance, rendering neutrophils the only leucocytes equipped with both gluconeogenesis and glycogenesis abilities (54)

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