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J Clin Investig 73:17851788 Zhang R, Zhang H, Zhang Z, Wang T, Niu J, Cui D, Xu S (2012) Neuroprotective effects of pre-treatment with l-carnitine and acetyl-l-carnitine on ischemic injury in vivo and in vitro

Additional therapies are needed to improve outcome after TBI in children

Alterations in acylcarnitine metabolism in the retina and retinal pigment epithelium/choroid tissue, especially decreased concentrations of short-chain or medium-chain odd-numbered acylcarnitine, may play a key role in accelerating the development of choroidal neovascularization and age-related macular degeneration [316]