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(d) validating the deep clustering model across pan-cancer datasets and other conditions.

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show that mTOR can regulate signaling through the insulin-like growth factor 1 receptor and that it possesses a new enzymatic activity the ability to phosphorylate proteins on tyrosine residues.

identify a role for Gstt1 in enhancing epithelialmesenchymal transition and disseminated tumour cell features in a subset of slow-cycling cells, thereby facilitating metastatic progression.