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The ROS generation ability of the membrane was reduced by 40% after gliotoxin treatment [29,59,60], and the in vitro addition of gliotoxin to flavocytochrome b558 and cytosolic components also exhibited an inhibition rate of 50% with the concentration of 3.3 M [60], suggesting that flavocytochrome b558 is the target of gliotoxin

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therefore, a mother's nutrition during pregnancy and lactation period is very important

[42] Low maternal vitamin B 12 , defined as serum concentration less than 148 pmol/L, increases the risk of miscarriage, preterm birth and newborn low birth weight